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Get Seal
Contributors
Seal is developed by:
and GitHub
Seal is developed by:
Although Seal doesn’t come with any guarantee of support or warranty, feel free to contact us if you have any problems installing or using it. We’ll try to help.
Seqal doesn’t run on 32-bit platforms
We have tested Seqal on 32-bit platforms and have found it not to run. We haven’t made this issue a priority since we expect most users to be running on a 64-bit platform.
Seal doesn’t handle single reads
At the moment PairReadsQSeq and Seqal only work with paired reads. If you want to align single reads, you can “hackishly” assemble a prq file that contains the same read as 1 and 2 and feed it to Seqal.
The alignment algorithm is implemented in libbwa, which is a modified and refactored version of the BWA short read aligner.
The Seal logo was pieced together from a seal image by mushko released in the Open Clip Art Library, and the Hadoop elephant.
If you use Seal in your work, please cite:
L. Pireddu, S. Leo, and G. Zanetti. MapReducing a genomic sequencing workflow. In Proceedings of the 20th ACM International Symposium on High Performance Distributed Computing, pages 67–74, June 2011.
Bibtex:
@inproceedings{seal_2011_mapred,
author = {Pireddu, Luca and Leo, Simone and Zanetti, Gianluigi},
title = {MapReducing a genomic sequencing workflow},
booktitle = {Proceedings of the second international workshop on MapReduce and its applications},
series = {MapReduce '11},
year = {2011},
isbn = {978-1-4503-0700-0},
location = {San Jose, California, USA},
pages = {67--74},
numpages = {8},
url = {http://doi.acm.org/10.1145/1996092.1996106},
doi = {http://doi.acm.org/10.1145/1996092.1996106},
acmid = {1996106},
publisher = {ACM},
address = {New York, NY, USA},
keywords = {MapReduce, next-generation sequencing, sequence alignment},
}
Seal is released under the GPLv3 license.